Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5e95156255d5fe8b2923c544786e176 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2018-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49f8019bd3af656298d6c9895f9b2a4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9e02469b16095ff987978b729d6f057 |
publicationDate |
2018-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2018204412-A1 |
titleOfInvention |
Systems-level analysis of tcga cancers reveals disease trna fragmentation patterns and associations with messenger rnas and repeat |
abstract |
Methods of treating a disease by leveraging positive and negative correlations between tRNA-derived fragments (tRF) and messenger RNA (mRNA) wherein said correlations can be used to establish a level of granularity that is specific to a disease of interest wherein said disease-specific positive and negative correlations can allow a level of therapeutic intervention that will be unprecedented because it will have been informed by three dimensions: at least one mRNA of interest; at least one tRF that are positively/negatively correlated with it; and, the identity of the disease in which one wishes to modulate the abundance of the at least one mRNA of interest. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11162101-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11434489-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112226507-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11008572-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112226507-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11326165-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020240162-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112522262-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11603531-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113924366-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020209590-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11091475-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11021708-B2 |
priorityDate |
2017-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |