Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_acc65fbc60e5240017a472e8c459dd33 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7052 |
filingDate |
2018-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2d766f0e290bf6b783a2d4aa1d250ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2e0b6e800ce869013e45b85050520fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34c6c6965c8b5f5d09c5c4773d259a01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f72c889a074bf42bb8a5b11072581f0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a4cb47205c75bd17ff1a6313a1be475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc1b8d8a471a27a9656ad501c8ed5289 |
publicationDate |
2018-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2018193116-A1 |
titleOfInvention |
Azithromycin derivatives containing a phosphonium ion as anticancer agents |
abstract |
This invention relates to compounds that are useful as cancer therapies. The compounds comprise azithromycin derivatives having a phosphonium cation tethered to the azithromycin macrocycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds. The compounds comprise an ion of formula (I): wherein either Z1 is and Z2 is OR3c; or Z2 is and Z1 is R2c. |
priorityDate |
2017-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |