| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aca280accfb8dcffabcb7e93d8351f18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d90b3f02a382ddd4a60ea36aeb9a638f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c1853f9c044abe3168bd2311f2f76ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a6f77cdf4d209ac84ce0341175639411 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5146
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5192
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-635 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 |
| filingDate |
2017-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_120848b19149bfa459d3b2b4c510d1de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f37a8544116f99da48a0765f903cde45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26e8efca666b0c3ea6fb6c86ff8fa8f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab4c113c6d842258d2078c85f0843fb6 |
| publicationDate |
2018-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018188136-A1 |
| titleOfInvention |
Method for preparing ultra-high drug-loaded nanoparticles by means of sequence precipitation-complex coacervation |
| abstract |
A method for preparing ultra-high drug-loaded nanoparticles by means of sequence precipitation-complex coacervation. The method comprises: first, mix a first reactant and a second reactant in a first reaction vessel (1), and then precipitate active pharmaceutical ingredients in the first reaction vessel (1) to form cores of drug nanoparticles; the reaction product in the first reaction vessel (1) quickly flows into a second reaction vessel (2) to mix with a third reactant; and after undergoing a complex coacervation reaction, shell materials are deposited on the surfaces of the cores of drug nanoparticles so as to form ultra-high drug-loaded nanoparticles having a core-shell structure. |
| priorityDate |
2017-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |