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filingDate 2018-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2018-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2018182039-A1
titleOfInvention Non-aqueous composition having drug carried therein, and method for producing same
abstract The present invention addresses the problem of providing: a non-aqueous composition having a drug carried therein, which can be prepared by mixing a drug-containing fat emulsion that can be used as an injectable solution, an eye drop, a nasal spray, an inhalant and the like with an aqueous medium upon use without needing to produce a drug-containing fat emulsion in advance; and a method for producing the non-aqueous composition. The non-aqueous composition having a drug carried therein according to the present invention, which is a solution for the problem, is characterized in that components are dissolved in a polyhydric alcohol that serves as a water-soluble carrier in such a manner that the content of an oil or fat can be 0.05 to 250 mg/g, the ratio of the content of a poorly-water-soluble drug to the content of the oil or fat (i.e., (poorly-water-soluble drug)/(oil or fat)) can be 0.0001 to 50 by weight (provided that the total content of the poorly-water-soluble drug and the oil or fat is up to 300 mg/g) and the content of an emulsifying agent can be 20 to 500 mg/g.
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