| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41ca9b060cc324d126a65f7b6f529acc |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
| filingDate |
2018-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfc9351c4a60802235e8768153d8873b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f50c756eb97cd96b2859251e7ca1ed7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1744841177f438a90c5fa1a69757313
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5171d57f7f9554cea7e87a806b59fb2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a51dcc5bf2fde4f3ceece30d5d5018e3 |
| publicationDate |
2018-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018178295-A1 |
| titleOfInvention |
Stable hot-melt extrudate containing valsartan and sacubitril |
| abstract |
The present invention relates to a solid unit dosage form for oral administration (tablet or granules) containing a solid dispersion of valsartan and sacubitril in a polymeric matrix. The solid dispersion is prepared by hot-melt extrusion and may contain the active ingredients preferably in a non-crystalline state. LCZ696, (pseudo)polymorphic forms thereof as well as the individual drugs, e.g. valsartan disodium and sacubitril monosodium, may be subjected to the hot-melt extrusion process. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023284724-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019239432-A1 |
| priorityDate |
2017-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |