| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4dc42489d4d5995ea72c0615204738c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate |
2018-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09ff5e104a3f44199da298fb82d42899
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ffadb9f363bf87533a9db1a31f6c553
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fe931478f7c9cf14ec0e74ff22fd56a |
| publicationDate |
2018-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018162563-A1 |
| titleOfInvention |
Mr1 restricted t cell receptors for cancer immunotherapy |
| abstract |
The invention relates to a method of isolating a T cell that expresses a T cell receptor capable of binding specifically to an antigen presented by a cancer cell in association with an MR molecule. The method comprises the steps of (a) providing a preparation of T cells, (b) contacting the preparation with cancer cells expressing MR1 protein; (c) isolating a T cell that is specifically reactive to said cancer cells. The invention further relates to a method of preparing a T cell preparation expressing select MR1 recognizing T cell receptors from transgene expression vectors, the use of such T cell preparations in treatment of cancer, and to collections of MR1 reactive T cell receptor encoding nucleic acids and cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022248881-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4039700-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4099015-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019081902-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11725039-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020053312-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11078252-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022118043-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023148494-A1 |
| priorityDate |
2017-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |