| abstract |
Provided are a humanized mouse model for hepatitis B constructed by using stem cells and an application thereof. The humanized mouse model for hepatitis B is constructed by means of obtaining human stem cells, implanting the human stem cells into a mouse with liver damage such that 1*10 4^8 transplanted human stem cells exist within the mouse body, and like steps; the present invention may be used in research on antiviral drug resistance, research on the pathogenesis of chronic hepatitis B, and like directions. |