| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4cc8283dd5112c85aeb567da229d0c3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0356
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0368
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0375
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0318 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
| filingDate |
2018-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1160be5d14c64dd904a6a82c83f489b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_313a6b3918e4ee4d5bc04919a99b46d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0cd2322a7d5a12f8144b439be7305f8 |
| publicationDate |
2018-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018159787-A1 |
| titleOfInvention |
Production method for disease model non-human animal, disease model non-human animal, drug screening method using disease model non-human animal, and disease risk determination method |
| abstract |
[Problem] The purpose of the present invention is to provide: a method for making an animal that has been stressed, and, in particular, chronically stressed, contract or present a specific disease or symptoms; and a tool that, by elucidating the process by which the stress leads to contracting or presenting the disease or symptoms, is useful for research and development related to the prevention or treatment of the disease or symptoms. [Solution] The present invention relates to: a production method for a disease model non-human animal that has inflamed intracerebral blood vessels; the disease model non-human animal; a drug screening method that uses the disease model non-human animal; a disease risk determination method that uses the presence of inflamed blood vessels as an indicator; and a pharmaceutical for preventing and/or treating progressive multiple sclerosis or the like. The present invention makes it possible to develop a pharmaceutical for the abovementioned disease or the like and to perform research to elucidate mechanisms of pathogenesis. The present invention also makes it possible to determine the risk of contracting or presenting progressive multiple sclerosis or the like and to prevent and/or treat progressive multiple sclerosis or the like. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11733232-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020045683-A1 |
| priorityDate |
2017-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |