| abstract |
The present invention establishes a technology for stably formulating an isoquinoline-6-amino derivative as an ophthalmic agent or the like. Provided is a medicinal preparation that is obtained by housing, in a polyester-based resin container or polyolefin-based resin container, an aqueous composition containing a compound represented by general formula (1) (in the formula: R 1 and R 2 each independently represent a hydrogen atom or a C 1 -C 4 alkyl group; R 3 represents a hydrogen atom or a hydroxyl group; "A" denotes -CH(R 4 )- or -CH 2 -CH(R 4 )-(here, R 4 is an optionally substituted C 6 -C 10 aryl group or an optionally substituted 5 to 10-membered heteroaryl group); and formula (1) also includes a tautomer thereof) or a salt thereof, or a solvate thereof. |