| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-50 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-244
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
| filingDate |
2018-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24db55bb07ecccd5d45731739982ac77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef2df4be63ac505ab69337f8e835e624
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2757d447e179251b65a6a518723e36b |
| publicationDate |
2018-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018158719-A1 |
| titleOfInvention |
Engineered heterodimeric proteins |
| abstract |
The present invention provides heterodimeric antibodies and fragments thereof and methods for their preparation, wherein the pairing of heavy and light chains has been improved. Interface residues were mutated such that each light chain strongly favoured its cognate heavy chain when two different heavy chains and two different light chains were co-transfected and co-expressed in the same cell to assemble a functional, heterodimeric antibody or fragment thereof. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020127376-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11161915-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020127354-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111655734-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023010219-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020221153-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022156687-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023169559-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021044361-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021044362-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113474368-A |
| priorityDate |
2017-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |