http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018158589-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82720f0fe09c6d788db8fde9be2350dc |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
| filingDate | 2018-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c86b56c7053b12bb77340218aa8e4c8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3520ff64d0c88d07dea698afe6e02e0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_536604dca2c9aa96b0b82139f871429a |
| publicationDate | 2018-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2018158589-A1 |
| titleOfInvention | Diagnostic and prognostic methods |
| abstract | The present invention relates to methods of diagnosing cervical cancer in an individual, involving determining the methylation status of Methylation Variable Positions (MVPs) in DNA from a sample from the individual and providing a diagnosis based on methylation status data. The invention also relates to methods of treating cervical cancer in an individual comprising providing a diagnosis of cervical cancer by the diagnostic methods defined herein, followed by administering one or more anti¬ cancer agents to the individual. The present invention also relates to methods of classifying a cervical cancer tumor from a patient having cervical cancer as being either a group 1 tumor or a group 2 tumor, wherein patients having a tumor assigned to group 2 are at risk of a poorer outcome following primary treatment regimes compared to patients having a tumor assigned to group 1. Such methods allow more efficient patient risk stratification for the purposes of providing further treatment and/or to help plan and manage patient care. The invention also relates to methylation-discriminatory arrays comprising probes directed to the MVPs defined herein, as well as kits comprising the arrays. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110257524-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021255461-A1 |
| priorityDate | 2017-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.