| abstract |
The present invention addresses the problem of finding a novel medicine that has an excellent tryptophanase inhibitory effect, that suppresses deterioration of renal functions by reducing indoxyl sulfate production in blood, and that contributes to kidney preservation. Provided is a medicinal composition containing, as an active ingredient, a compound represented by formula (I) or a pharmacologically acceptable salt thereof. [In the formula, R 1 and R 2 may be the same or different, and each represent a C 1 -C 6 alkyl group, a halogeno C 1 -C 6 alkyl group, or a C 3 -C 6 cycloalkyl group; n is 0, 1, or 2; X represents a C 1 -C 6 alkyl group, a C 3 -C 6 cycloalkyl group, a halogen atom, or the like; Y represents a hydrogen atom, a C 1 -C 6 alkoxy group, a C 3 -C 6 cycloalkoxy group, or a halogeno C 1 -C 6 alkoxy group.] |