Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a05a09d28a284fc55862088ef711de7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b7ed1187723440f103af52a9185eed4 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7028 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
filingDate |
2018-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76bed4338d718a6e07342560948b8205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_792f894ef41d80bc1c633d56309036dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58a70b58c284cfbaa487fead85906648 |
publicationDate |
2018-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2018155051-A1 |
titleOfInvention |
Lipid a |
abstract |
Provided is lipid A, which has a novel structure. More specifically, provided is lipid A which can be used in an adjuvant, and with which side effects such as allergic reaction and inflammation are reduced, while maintaining an excellent immunological activation ability. Also provided is an adjuvant composition including lipid A. Lipid A is characterized by comprising a complex of a glucosamine disaccharide chain and fatty acid chains. Lipid A is further characterized in that: 3-hydroxy fatty acid chains are bonded to positions 2 and 2' of the glucosamine disaccharide chain; and a secondary fatty acid chain comprising a 3-hydroxy fatty acid chain is further bonded to at least one of the 3-hydroxy fatty acid chains. The adjuvant including lipid A inhibits side effects such as allergic reaction and inflammation, while maintaining excellent immunological activation action in comparison to adjuvants known in the prior art. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102020100021-A1 |
priorityDate |
2017-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |