http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018153325-A1

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filingDate 2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6ee1a6b17ed79535f4cb7c7c12c5e8c
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publicationDate 2018-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2018153325-A1
titleOfInvention Biflavonoid-cobalt complex, preparation method for same, and applications thereof
abstract Disclosed are a biflabonoid-cobalt complex, a preparation method for same, and applications thereof. The present invention has amentoflavone as a ligand and a cobalt ion as a central ion, produces an amentoflavone-cobalt complex via a reaction, and characterizes the structure of the complex using infrared spectroscopy, ultraviolet-visible absorption spectroscopy, and high-resolution mass spectrometry. At the same time, the present invention researches antitumor and antioxidant activities of the amentoflavone-cobalt complex. MTT method indicates that the amentoflavone-cobalt complex is provided with improved antitumor activity, and the antitumor activity is stronger than that of amentoflavone; pyrogallol self-oxidation method, ABTS method, and FRAP method indicate that the antioxidant activity of the amentoflavone-cobalt complex is stronger than that of amentoflavone itself. The formation of the amentoflavone-cobale complex increases the antitumor and antioxidant activities of amentoflavone and is expected to be applicable in the development of a medicament.
priorityDate 2017-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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