| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4f7112981646478d623f9b869f7c771
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06dd9a691a7f564db666af5972b6683e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9f9b1ecc7f1d2adb93fe7ac938fb17b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24162
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24121
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-555
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24134 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 |
| filingDate |
2018-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89ef3b1fd4c838de57691ce4dcc54913
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3ce4ef47436b12661d8d98ca1da69a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_505cf72afbaae6d0cb1a43bf22fc14da |
| publicationDate |
2018-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018152158-A1 |
| titleOfInvention |
Live attenuated zika virus with 3'utr deletion, vaccine containing and use thereof |
| abstract |
The present invention discloses a live attenuated strain of Zika virus (ZIKV) having a deletion in the 3' untranslated region (3'UTR) of the viral genome, which may affect viral RNA synthesis and sensitivity to type I interferon inhibition, but may not affect viral RNA translation. The present invention also discloses the use of these live attenuated ZIKV strains in the preparation of ZIKV vaccines and for providing immunoprotection against ZIKV infection and congenital ZIKV syndrome, particularly in pregnant females. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022135425-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021191688-A1 |
| priorityDate |
2017-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |