Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2291-0423 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2291-0426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0442 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N29-222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H10N30-10513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H10N30-80 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01L41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N29-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N29-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01L41-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01L41-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01L41-04 |
filingDate |
2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd1c7060cb76f23d76e1a8f0fdb7701f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6575cb226d1f534f7c39eb129265cf77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eeb85c415b2a86ee24a78d6fdce4d3ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7695acee6850df0946c49274cb492eef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8da4dfc2e8f48e766220ce51d2fcfba2 |
publicationDate |
2018-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2018148715-A1 |
titleOfInvention |
Device and method for intracellular delivery of biomolecular cargo via acoustic wave exposure |
abstract |
A microfluidic-based device and system is disclosed for the high-throughput intracellular delivery of biomolecular cargo to cells (eukaryotic or prokaryotic) or enveloped viruses. Cargo integration occurs due to transient membrane permeabilization by exposure to bulk acoustic waves (BAWs) transduced from surface acoustic waves (SAWs) generated by a rapidly oscillating piezoelectric substrate. In this approach, temporary pores are established across the cellular membrane as cells are partially deformed and squeezed or subject to shearing forces as they travel through the vibrational modes created within the microfludic channel(s) of the device. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020037238-A1 |
priorityDate |
2017-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |