| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cda24a652f0649c1486eab7998f81c71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_077209f9cfeac17d8a084da546a6c532
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9ab700e3fd932b7ccc18d8ea4ec29dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_910ef5c85e4bf91537ee87d95b0c7418
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02ac6d88176ca78153f908b2112f3af5 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7072 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 |
| filingDate |
2018-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23c136b772dd6105ab76ffb58188b2d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d62c5b610fab1865c737de691356a356
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_792cce9f81f5531b6302f470b0ffe67e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4f09decfd12af26bc37794023be1210
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0af24cc8d07cd90b11617e9e8600072 |
| publicationDate |
2018-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018143893-A1 |
| titleOfInvention |
Idoxuridine and its analogs as neuroprotectans for the treatment of parkinsonism |
| abstract |
The invention relates to compounds that are useful in the treatment of parkinsonism, such as parkinsonism in connection with Parkinson's disease (PD); dementia with Lewy bodies (DLB); multiple system atrophy (MSA); corticobasal degeneration (CBD); or progressive supranuclear palsy (PSP). The said compounds include in particular idoxuridineand analogs thereofas well as their metabolic precursors, such as ropidoxuridine.The invention further relates to method for identifying compounds useful for the treatment of parkinsonism, said methods comprising detecting the capability of compound to increase the amount of GPR37 in cell membranes.The invention further relates to methods for the chemical synthesis of ropidoxuridine. |
| priorityDate |
2017-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |