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filingDate 2018-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e39532536710dab79bb2e970e933be8e
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publicationDate 2018-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2018139679-A1
titleOfInvention Nucleic acid drug capable of inhibiting invasion and metastasis of cancer, and cancer biomarker
abstract Disclosed is an anti-tumor agent comprising a SNORA23 gene expression inhibitor. The SNORA23 expression inhibitor may be an oligonucleotide containing at least one nucleoside structure represented by formula (1) (wherein each of "Base" and "A" represents a specific substituent or structure) or a pharmacologically acceptable salt thereof. Also disclosed is an anti-tumor agent comprising an SYNE2 gene expression inhibitor. Also disclosed is a use of SNORA23 as a biomarker, said use being characterized in that SNORA23 in a blood sample is measured for the purpose of detecting the occurrence of invasion or metastasis of a tumor.
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priorityDate 2017-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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