abstract |
Provided are a novel use of 1,2-di-O-galloyl-4,6-O-(S)-hexahydroxydiphenoyl-β-D-glucose (hereinafter abbreviated as "GHG") which is contained in a large amount in purple tea produced in Kenya (scientific name: Camellia sinensis , variety name: TRFK306); and a novel circadian rhythm regulator which is widely usable as medicines, beverages, foods and cosmetics. The circadian rhythm regulator according to the present invention is characterized by comprising GHG as an active ingredient having an effect of promoting the expression of Bmal1 gene. Also, the circadian rhythm regulator according to the present invention is characterized by comprising a GHG-containing extract derived from the purple tea produced in Kenya as an active ingredient having an effect of promoting the expression of Bmal1 gene. |