http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018137959-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0bf0928b608797b70bbc2b91c7e52e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-79 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 |
| filingDate | 2018-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0c8b583a1574cd2e89284549b969704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4cbf5fb09d86d2816cbce11cf8922f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_564f8f3860ea8f8be4606ef15d4efae4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d06db1a4050595aee10fe12f44afbd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_233c0c98d8e20f1913f0e70d074e3a3b |
| publicationDate | 2018-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2018137959-A1 |
| titleOfInvention | Process for preparation of benzylic amides |
| abstract | The present invention relates to a process for preparing benzylic amides of formula (I) wherein the variables have the meaning as defined in the description, by reductive amidation of a nitrile of formula (II) wherein the variables have the meanings given for formula I, with an activated carbonyl compound of formula (III), and which nitrile is obtained by reaction of a compound of formula (IV) with a halogen compound of formula (V), wherein X is a halogen atom, preferably bromo, which halogen compound V in turn is obtained by Sandmeyer reaction of an aniline derivative of formula (VI) novel compounds of formula (I), and processes for preparing compounds of formula (XII) wherein the variables have the meaning as defined in the description by condensing compounds of formula I with compounds of formula (X) and subjecting the resulting α,β-unsaturated ketone of formula (XI) to a reaction with hydroxylamine to yield compounds of formula (XII.) |
| priorityDate | 2017-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 465.