Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33a62710796e131599043055d399597f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-986 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D477-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-14 |
filingDate |
2018-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de84b57bb73f1428a052f06df4191340 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_818928f3fd9ee735dea65dd11c40337e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68a80e799a911a576a71d68597b8473a |
publicationDate |
2018-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2018130158-A1 |
titleOfInvention |
Carbapenem antibiotic-tolerant pathogenic bacterium fluorescent probe and synthesis method and use thereof |
abstract |
Disclosed in the present invention is a carbapenem antibiotic-tolerant pathogenic bacterium fluorescent probe with a structural general formula as represented by general formula I. The synthesis method for the fluorescent probe comprises the steps of: (1) preparation of a compound 3; (2) preparation of a compound 4; and (3) preparation of a fluorescent probe CVB-1. The fluorescent probe can be made into a test paper, kits or detection chips to be applied to the detection of carbapenemases and carbapenem drug-tolerant bacteria. Carbapenemases are detected or distinguished by determining whether the fluorescence intensity or colour of the fluorescent probe changes or not, and accordingly, pathogenic drug-tolerant bacteria expressing carbapenemases can be detected rapidly. The fluorescent probe guides the reasonable utilization of antibiotic drugs in terms of treatment or clinical application, and has important significance in terms of using no or less antibiotic drugs. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113218928-A |
priorityDate |
2017-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |