| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b775791237e8a932aa275824c2eefcab |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
| filingDate |
2018-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3dc33541be04dbb54a7ab04b3d60bce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bb1615b4f647002c51dbb07f60146c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2770e68f4f8753a10ab2f4dda4b0f1e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c7a5406a4517947a4f42b659e0b5dad |
| publicationDate |
2018-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018129544-A1 |
| titleOfInvention |
Methods of altering gene expression by perturbing transcription factor multimers that structure regulatory loops |
| abstract |
The invention relates to methods of modulating the expression of one or more genes in a cell by modulating the multimerization of a transcription factor and/or modulating the formation of enhancer-promoter DNA loops, and thereby modulating the expression of the one or more genes. The invention also relates to treating diseases and conditions involving aberrant gene expression by modulating the multimerization of a transcription factor and/or modulating the formation of enhancer-promoter DNA loops. The invention also relates to methods for screening for compounds that modulate expression of one or more genes in a cell. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3967760-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11493519-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11624065-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022053606-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11312955-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11340231-B2 |
| priorityDate |
2017-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |