http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018128408-A1

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filingDate 2018-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df9c5972b65a1ef4cbe083e607b283be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38cb8a419e64909a07053f122e87c468
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publicationDate 2018-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2018128408-A1
titleOfInvention Pharmaceutical composition for preventing or treating allergic diseases such as asthma or atopy, comprising baicalein as active ingredient
abstract The present invention relates to a pharmaceutical composition for preventing or treating allergic diseases such as asthma or atopy, the composition comprising, as an active ingredient, baicalein for controlling thymic stromal lymphopoietin (TSLP)- mediated signaling. According to the present invention, a baicalein substance extracted from Scutellaria baicalensis was confirmed to control intracellular signal transduction by TSLP, thereby inhibiting intracellular STAT5 phosphorylation and inhibiting a reaction between TSLP and TSLPR, and thus a pharmaceutical composition may be provided that is capable of effectively inhibiting the formation of inflammatory responses of allergic diseases or asthma. In addition, a pharmaceutical composition may be provided that further comprises a compound having a synergistic effect with baicalein, thereby being capable of more effectively inhibiting the formation of inflammatory responses of allergic diseases such as asthma or atopy.
priorityDate 2017-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 41.