http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018124642-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4820e6ded4d368fa1fde368d6f96f753 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-1361 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0654 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0664 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0607 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
filingDate | 2017-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f4bb417690aa1c11164a810319488a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89d224e7098a51d0a5f809fff9d1f2ab |
publicationDate | 2018-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2018124642-A2 |
titleOfInvention | Composition for differentiation of dental pulp stem cells into odontoblast progenitor cells and igg or igm type monoclonal antibody specifically binding to surface of odontoblast progenitor cells |
abstract | The present invention relates to a composition for differentiation of dental pulp stem cells into odontoblast progenitor cells and an IgG or IgM type monoclonal antibody specifically binding to the surface of the odontoblast progenitor cells differentiated from the dental pulp stem cells. According to the present invention, when BMP2 and BMP4 are treated in combination at an optimal ratio, the differentiation efficiency of the dental pulp stem cells into the odontoblast progenitor cells is significantly increased, the calcification of a matrix is induced, and the ability of the odontoblast progenitor cells to be differentiated into dentin is enhanced. In addition, when an IgG or IgM monoclonal antibody that specifically binds to the surface of the odontoblast progenitor cells of the present invention is employed, the odontoblast progenitor cells that can be usefully used for tissue regeneration and differentiation can be effectively isolated and purified. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110563807-A |
priorityDate | 2016-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 448.