http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018123764-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad23ecf473f76fdb0ed90e87ed0e312f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1096 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2017-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c00e99f3cc14a9981ec791a2ce173b6e |
| publicationDate | 2018-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2018123764-A1 |
| titleOfInvention | Reagent for use in assessment of remaining very small lesion of neuroblastoma; and method for analyzing biological sample using same |
| abstract | Provided is a combination of gene markers, which enables the highly sensitive detection of a remaining very small lesion of neuroblastoma even in a sample in which the amounts of genes expressed are small. A reagent according to the present invention comprises a primer pair capable of amplifying each of gene markers CRMP1, DBH, DDC, GAP43, ISL1, PHOX2B and TH by a nucleic acid amplification method, and can be used for the assessment of a remaining very small lesion of neuroblastoma. The reagent may additionally contain a primer pair capable of amplifying HPRT1 gene by a nucleic acid amplification method. A method for analyzing a biological sample according to the present invention comprises a step of measuring the amount of each of gene markers CRMP1, DBH, DDC, GAP43, ISL1, PHOX2B and TH expressed in the biological sample by a nucleic acid amplification method using the reagent. It is preferred that the nucleic acid amplification method is carried out by a digital PCR. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022183483-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021006345-A1 |
| priorityDate | 2016-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1346.