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filingDate 2017-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab42bb09d3b4a869cb645c0c5b2d4766
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publicationDate 2018-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2018119493-A1
titleOfInvention A synthetic implantable scaffold
abstract The present invention provides a synthetic implantable scaffold comprising a plurality of polymer fibres in contact with a composition comprising a hydrogel-forming polymer and a biocompatible ceramic material. Preferably the polymer fibres are formed from ultra-high molecular weight polyethylene (UHMWPE) and are in the form of a bundle of fibres. Preferably the implantable scaffold comprises a plurality of bundles of individual polymer fibres, which may be in the form of a braid. The hydrogel-forming polymer is preferably polyvinyl alcohol for mimicking the fibre-ECM hierarchical structure of native tendons or ligaments. The biocompatible ceramic material is preferably Hardystonite (Ca 2 ZnSi 2 O 7 ) doped with Sr, Mg or Ba. The synthetic implantable scaffold of the invention is particularly suited as a synthetic ligament or tendon. The invention also relates to a method for preparing a synthetic implantable scaffold, and use of the implantable scaffold for partial or full tendon or ligament repair.
priorityDate 2016-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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