Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac31afbea1cbbb03498644721ffb4a62 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0306 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0278 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
filingDate |
2016-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_036fe7dbb720c7c2226605e609104402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc8f83241ca79a97bff5f3e775353397 |
publicationDate |
2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2018112815-A1 |
titleOfInvention |
Animal model for hearing loss syndrome and treatment method thereof |
abstract |
A transgenic mouse whose genome includes a disruption of Pou4f3 gene exhibits reduced hearing ability as compared to hearing ability of a wild-type mouse and/or exhibits a symptom of DFNA15 disease. A method for preparing a transgenic mouse is provided. A method of reducing one or more symptoms of the DFNA15 disease of a subject includes administering to the subject an amount of an agent that inhibits a retinoid acid signaling pathway of the subject. |
priorityDate |
2016-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |