Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99316837ebc5b77a725eb97d2091113a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43518 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
filingDate |
2017-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c31c4c7aa9d56c19b19443c3deff57a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_267ebf0dd6bf83397832bfa022f45286 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11e79b00b8fa3fd1f6cc556b3099deb0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6e1ba10cdd99caf037441849810b894 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b8001c1d5d4aca004c0d50a4a7ceb1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7abceb539761b13b612243c60f2d7ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f148c21044b7fe630485b474f332086 |
publicationDate |
2018-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2018106142-A1 |
titleOfInvention |
Peptide modulator of purinoceptors |
abstract |
The invention relates to medicine and pharmacology, specifically to biologically active peptides that modulate purinergic signaLling. To this end, a peptide is proposed that has the following amino acid sequence: Gly 1 -Tyr 2 -Cys 3 -Ala 4 -Thr 5 -Lys 6 -Gly 7 -Ile 8 -Lys 9 -Cys 10 -Asn 11 -Asp 12 -Ile 13 -His 14 -Cys 15 -Cys 16 -Ser 17 -Gly 18 -Leu 19 -Lys 20 -Cys 21 -Asp 22 -Ser 23 -Lys 24 -Arg 25 -Lys 26 -Val 27 -Cys 28 -Val 29 -Lys 30 Gly 31 , or a sequence at least 90% homologous thereto. Peptides according to the invention can be used to prevent and treat purinoceptor-mediated diseases. Said peptides can be used to develop new medicinal agents based thereon, for example analgesics, and can also be used to study pain mechanisms and to identify and test new P2X3 receptor modulators. Peptides according to the invention can be produced by chemical synthesis or biotechnologically on the basis of the nucleotide sequence of the corresponding gene. |
priorityDate |
2016-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |