| abstract |
An oral composite tablet and a method of preparing the same are provided. The oral composite tablet includes: an ezetimibe wet granule portion including ezetimibe; and a rosuvastatin mixture portion including rosuvastatin or a pharmaceutically acceptable salt thereof, wherein the ezetimibe wet granule portion includes, as a binder, povidone having a weight average molecular weight of about 30,000 to about 50,000, and the rosuvastatin mixture portion includes a diluents including a water-soluble diluent and a water-insoluble diluent, the water-insoluble diluent having a particle size (d90) of about 98 μm to about 229 μm corresponding to 90% in a cumulative particles size distribution of total particles. |