http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018100096-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b01dcd61775e996fac631d4b10c4e87f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_048e5039af40d0702600074cbd2d8986 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-347 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2017-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90de180d13c65e2dc79925e687ed49d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34a13c80dc3fa3a99c7a8c2d78845949 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cba7e11c6538a6556dd06e121ad5399 |
publicationDate | 2018-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2018100096-A1 |
titleOfInvention | Use of anti-uchl1 igg plasma concentration for diagnosing idiopathic steroid sensitive nephrotic syndrome |
abstract | The present invention relates to methods and kits for diagnosing Idiopathic steroid sensitive nephrotic syndrome. The inventors showed that idiopathic nephrotic syndrome (INS) patients display a significant plasma level of anti-UCHL1 IgG that target the podocytes. Based on the correlation between the plasma level of anti UCHL1 IgG and proteinuria, they suggested that anti UCHL1 IgG plays a central role in the development of massive proteinuria. In particular, the present invention relates to a method of determining whether a subject suffers from idiopathic steroid sensitive nephrotic syndrome (INS) comprising i) determining the concentration of plasma anti-UCHL1 IgG in a sample obtained from the subject ii) comparing the concentration determined at step i) with a predetermined reference value and iii) concluding that the subject suffer from idiopathic steroid sensitive nephrotic syndrome when the concentration determined at step i) is higher than the predetermined reference value. |
priorityDate | 2016-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1870.