| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37b416a8c0d2b0f1c3d6026d932027af |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y603-01002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-203 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y603-01002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 |
| filingDate |
2017-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a82107bd5534b682cc8c52042499188
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bedf1a72d9240607126da398f9e6dab6 |
| publicationDate |
2018-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018093331-A1 |
| titleOfInvention |
Attenuated glutamine synthetase as a selection marker |
| abstract |
The invention relates to an expression vector comprising a polynucleotide encoding a mutated glutamine synthetase (GS) with reduced activity, and the GS mutant is used as a selection marker in a method for producing a polypeptide of interest wherein the addition of GS inhibitor may not be required. Also disclosed the GS mutant comprising one or more mutations in the glutamate binding region, the ATP binding region and/or the ammonia binding region. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023180398-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023180374-A1 |
| priorityDate |
2016-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |