Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd5626cc1b172236e1be7678d60a7b42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b56e939c513a4c1d78ee9d7593934 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M1-3486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2529-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-734 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0644 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02 |
filingDate |
2017-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57eb035ecfaf2f6a18d4fcb79703e8dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ab4988c3bfa40f749881370dccaf5c2 |
publicationDate |
2018-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2018091713-A1 |
titleOfInvention |
A method for preparing a growth factors containing platelet releasate |
abstract |
The present invention relates to a method for preparing a growth-factors containing platelet releasate from a fluid mammalian platelet concentrate, comprising the consecutive steps of subjecting the platelet concentrate to a pathogen reduction step to disrupt non-enveloped viruses; subjecting the platelet concentrate to an activation step to cause the platelets to release growth factors; recovering a fibrinogen depleted fluid platelet releasate; subjecting the fibrinogen depleted fluid platelet releasate to a second pathogen concentration reduction step to disrupt enveloped viruses; subjecting the platelet releasate to sterile filtering and recovering a filtrate liquid containing the growth factors. The platelet releasate obtained with the method of the present invention may be used as a therapeutic agent to enhance the proliferation of multi lineage cells in regenerative medicine and in the management of non healing wounds and resistant ulcers. The second indication is as a substitute to fetal bovine serum in in cell culture media. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3700630-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021035205-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021199041-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023026213-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113573718-A |
priorityDate |
2016-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |