abstract |
Disclosed are a polymorphic form of a GnRH receptor antagonist and a preparation method therefor. In particular, disclosed are polymorphic forms A, B, C, and D of 1-(4-(7-(2,6-difluorobenzyl)-3-((dimethylamino)methyl)-5-(6-methoxypyridazin-3-yl)-4,6-dicarbonyl-4,5,6,7-tetrahydro-2H-pyrazolo [3,4-d] pyrimidin-2-yl)phenyl)-3-methoxyurea (a compound of formula (I)) and preparation methods therefor, the use thereof in pharmaceutical compositions, and the use of the polymorphic forms and compositions in preparation of drugs for treating and/or preventing diseases associated with GnRH receptor antagonists. |