| abstract |
The present invention is directed to the use of Deterministic Lateral Displacement (DLD) in the preparation of cells and compositions for therapeutic uses. The present invention is directed, inter alia, to methods of collecting and rapidly processing cells, particularly cells that have therapeutic uses. The invention is directed to a method of genetically engineering a population of target cells comprising isolating target cells from a crude fluid composition by performing DLD using a microfluidic device. The invention includes a method of producing CAR T cells by obtaining a crude fluid composition comprising T cells. |