| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c87b1f7158bec499783fa1b27aad08c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2017-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90200bb52dd16a3391c55afbf80bc5ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ebefeb6076efe51a0ef8b3685d13012
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_143a35739b0f7474d8b036f358d971d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c29c144164b42d55d8b13783523d745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eedfdc31aabbafe76919b05e047b8b01 |
| publicationDate |
2018-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018067075-A1 |
| titleOfInvention |
Compositions and methods for protein expression and delivery |
| abstract |
The present invention relates to methods and compositions that provide an environment that promotes enhanced protein expressing and/or folding. More particularly, the present invention provides engineered thermostable ferritin assemblies comprising at least one modified ferritin subunit, wherein the least at least one modified ferritin subunit lacks an unstructured carboxy-terminal sequence that is present in a wildtype ferritin subunit and wherein the engineered assembly is stable at lower salt concentrations that a wildtype ferritin assembly. The invention is exemplified by a ferritin assembly derived from hyperthermophilic Archaeoglobus fulgidus. Also claimed are nucleic acids, compositions, kits and methods of encapsulating a polypeptide, delivering and administering the said engineered ferritin assembly to a subject. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112094861-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019193594-A |
| priorityDate |
2016-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |