| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0b9b9c852ed547d55dd16c053269b29 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5138
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M31-002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F13-124
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-626
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-624 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-0017
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02C7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0051 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02C7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 |
| filingDate |
2017-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f8a89da4d425eeaaa95186f34b05e4c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64dcfd2afb946b7f8d3aabcf10c8dcf3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa85d3252375d99687b439f890b75976 |
| publicationDate |
2018-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018064578-A1 |
| titleOfInvention |
High-precision drug delivery by dual-domain ocular device |
| abstract |
The present invention relates to a nanocomposite ocular device that can release drugs within a close distance to the ocular surface and provide controlled and sustained release of the drug at a constant rate. The device can achieve both optical and medical functions. The device comprises a drug, one or more reservoir domains, and a barrier layer configured to block the drug diffusion paths from the reservoir domain to the ocular surface in the eye of the subject, wherein the drug partitions between the reservoir domain and the barrier layer, and the equilibrium drug solubility in the reservoir domain is at least five folds higher than that in the barrier layer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11617681-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11298262-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109091299-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109091299-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022096373-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021173662-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11399977-B2 |
| priorityDate |
2016-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |