http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018064571-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7de02e4b28736bfb52de8bb358be203e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2440-34 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-104 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5017 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y203-02008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 |
| filingDate | 2017-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a34c9d4f2949dc8d6623702fb1575e53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f20b2e9d957faa7f0c12d253cd9c4f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8fa14e3568fe6ee80cd1709fcbbc7b6 |
| publicationDate | 2018-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2018064571-A1 |
| titleOfInvention | Methods to detect dna mutagenesis |
| abstract | The disclosure provides a method comprising introducing into a cell an expression vector comprising a nucleic acid sequence encoding a reporter protein fused to an arginyltransferase 1 substrate; measuring arginylation and reporter protein levels; and calculating the ratio of arginylated substrate to reporter protein; and a method comprising introducing into a cell a reporter plasmid comprising a nucleic acid encoding a promoter, a first reporter protein, an internal ribosome entry site (IRES), and a second reporter protein, wherein the nucleic acid encoding the first reporter protein comprises a premature stop codon and mutation of the stop codon results in first reporter protein expression, or the nucleic acid encoding the second reporter protein comprises a premature stop codon and mutation of the stop codon results second reporter protein expression; measuring the first reporter protein and the second reporter protein; and calculating the ratio of first reporter protein to second reporter protein. |
| priorityDate | 2016-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 252.