Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b511d66a5a91e0e20440583ed11c3fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdd959ff721762980b9e755cdac44de8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2521-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2513-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M41-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M29-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0643 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0654 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0075 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09 |
filingDate |
2017-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3c6b129edad000bd82e6a30ecac1bc7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3ba4632bda8e33a5c76553ab7d45145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56b68c6295bca4b7b21076b74359daff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab43ec0fbc28f5a7443c6b59f6643d3e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b13dc6df5ecc5823e596849fd8dc68c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3cb90b2db6c787f77b240678fd74661 |
publicationDate |
2018-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2018064440-A1 |
titleOfInvention |
Well plate-based perfusion culture model of endosteal-, extracellular matrix (ecm)- and endothelial- myeloma interactions and methods for testing personalized therapeutics for multiple myeloma |
abstract |
The described invention provides a well plate-based perfusion culture model of endosteal-, extracellular matrix (ECM)- and endothelial- myeloma interactions and patient-specific methods for selecting treatment for and assessing drug resistance of multiple myeloma (MM). The described methods utilize an ex vivo three dimensional endosteal microenvironment effective to recapitulate spatial and temporal characteristics of a multiple myeloma cancer niche and to maintain viability of multiple myeloma cells (MMCs) obtained from a patient suffering from MM. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020113210-A1 |
priorityDate |
2016-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |