| abstract |
The present invention relates to a lacosamide sustained release preparation and, more specifically, to a lacosamide sustained release preparation which is composed of a sustained release matrix of a mucoadhesive polymer and a water-soluble diluent and exhibits the effect of maintaining a constant drug release rate even in various pH ranges of the gastrointestinal tract. The lacosamide sustained release preparation according to the present invention can effectively control the in-vivo release of an active substance by controlling the ratio and particle size of the mucoadhesive polymer, and thus can easily control the concentration of a drug in blood, and can be useful as a sustained drug delivery system for oral administration by attaching the mucoadhesive polymer to the mucosa of the gastrointestinal tract. |