abstract |
The present invention relates to a brazzein multiplex variant having antiallergic and antioxidative activities and, more specifically, to a brazzein multiplex variant capable of simultaneously exhibiting both an antioxidative effect through GST and tyrosinase activities and an antiallergic effect through an inhibitory activity against the release of β-hexosaminidase, which is a degranulation-indicating substance, released with histamine. Accordingly, the brazzein multiplex variant according to the present invention can be usefully employed in a pharmaceutical composition for allergic disease prevention or treatment, an antiallergic cosmetic composition, an antioxidative composition, an antioxidative cosmetic composition, and a health functional food. |