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filingDate 2017-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af3fb4aadab5d7149ce5d53465fa6955
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_273a50aee8e7290087156f8d70ff8202
publicationDate 2018-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2018055200-A2
titleOfInvention Polyurethane-hydrogel composition comprising chlorhexidine
abstract The invention is directed to a composition comprising: a polyurethane substrate; a hydrogel forming polymer on at least one of the two faces of the polyurethane substrate; and chlorhexidine on the at least one face comprising the hydrogel forming polymer; wherein the hydrogel polymer is covalently linked to the polyurethane substrate. The invention is also directed to a dressing comprising the composition and to a process for the preparation of the composition, the process comprising the following steps: a) impregnating at least one face of a polyurethane substrate with a solution comprising a reactive diolefin and a free radical initiator; b) extracting the polyurethane from the solution and, after drying, immerging the polyurethane in a solution containing the initiator catalyst and the hydrogel forming polymer to obtain PU covalently bond to a hydrogel forming polymer; c) extracting the polyurethane-hydrogel composition and drying in air; d) immerging the product of step iii) into an aqueous solution of chlorhexidine; e) collecting the polyurethane-hydrogel-chlorhexidine product from the solution and drying the obtained composition in air.
priorityDate 2016-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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