http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018046243-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_30a7bcefaec4efdf749c936726d5d64a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a61c11d10dd703b85946a6f210e064f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d47ea4a98d4d599e0ff810991424307 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-02 |
filingDate | 2017-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e5be3610d3e754b682efddc6210e9bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bc23ed48139fa320259cc13d0dcf256 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a44f4e2949fe6377e2f259c5f07b5e0 |
publicationDate | 2018-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2018046243-A1 |
titleOfInvention | Compounds for reducing cellular melanin content |
abstract | The present invention relates to molecules capable of reducing cellular melanin content; in particular to reducing melanin content for applications in fields such as skin lightening. There is a continuing need for new cosmetic skin lightening agents, with improved overall effectiveness. It is therefore an object of the present invention to provide a compound that acts as a melanin content reducer. It is found that specific indolyl compounds can reduce the melanin content in the melanocytes. Disclosed is use of a compound of formula (I) or a salt thereof, for reducing cellular melanin content of human skin, where, (i) R is: (a) - (CH 2 ) n - A, where n = 1 to 6 and A is -OH or -NH2; or b) - O-(CH 2 ) n - X, where n = 1 to 5 and X is a halogen; (ii) R 2 is -H, alkyl, n-hexyl, aryl, alkoxy or aryloxy group; and, (iii) R 3 is -H, alkyl, aryl, alkoxy or aryloxy group. |
priorityDate | 2016-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 363.