| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3dded61bd89f99900518597c0958b9a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_266f27c9e90e00b1173c45726524c540 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-32 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-502 |
| filingDate |
2017-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a854e5c82782b7a316b39f08aa1aca2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78d37c42214fc2eb5eddf039ee6c05c6 |
| publicationDate |
2018-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018038680-A1 |
| titleOfInvention |
Processes for preparing olaparib |
| abstract |
Provided herein are novel processes and methods for making 4-[(3-[(4-cyclopropylcarbonyl)piperazin-1-yl]carbonyl)-4-fluorophenyl]methyl(2H)phthalazin-1-one (Olaparib) and intermediates thereof. Olaparib is a poly ADP ribose polymerase (PARP) inhibitor useful in the treatment of of cancers. Benefits of the present disclosure include the use of less toxic compounds and improved yields. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023017393-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021220120-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022215034-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022090938-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113234024-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10100017-B2 |
| priorityDate |
2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |