abstract |
The invention relates to compounds of formula (I): wherein Q, A 1 , A 2 , A 3 , A 5 , A 6 , A 7 , A 8 , R 4b and R 5 are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over-activation of NF-kB signaling is observed. |