| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba8362c1deb8fba6d04a2dd8972d4078 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-526 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-468
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1018 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46 |
| filingDate |
2017-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d2a73f4e1bb2e2afacd3fac2d3eaba2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3885becc7a3fd1e4562732d5d1420a44 |
| publicationDate |
2018-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018016881-A1 |
| titleOfInvention |
Bispecific proteins and methods for preparing same |
| abstract |
The present invention relates to a bispecific protein and a preparation method therefor and, more specifically, to a bispecific protein with a purity of heterodimers which is prepared by introducing a mutation into a heavy chain and/or a light chain to thus increase a heterodimer formation rate between a heavy chain (CH3 domain or Fc) and a heavy chain (CH3 domain or Fc) and increase a dimer formation rate between chains targeting the same material between a heavy chain (CH1 domain) and a light chain. The bispecific protein according to the present invention is useful in various fields such as cancer treatment, signal regulation, diagnosis, etc. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11773176-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10450381-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10759870-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019065795-A1 |
| priorityDate |
2016-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |