| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a48b4ddb10c7a242d43dc564d97885e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_680dd0699e3f4ba8532d128c7152b3bb |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D335-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B23-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0032
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B57-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D335-12 |
| filingDate |
2017-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca861a9c0900dfcd8ad63fb489d35746
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14fc885605f51b3d7cff3400162b4572
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4436314dacce639e10e4547f96b04cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ff8822f0443fc84e7702d5c132de253 |
| publicationDate |
2018-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018013930-A1 |
| titleOfInvention |
Mechanical opening of lipid bilayers by molecular nanomachines |
| abstract |
Embodiments of the present disclosure pertain to methods of opening a lipid bilayer by associating the lipid bilayer with a molecule that includes a moving component capable of moving (e.g., rotating) in response to an external stimulus; and exposing the molecule to an external stimulus before, during or after associating the molecule with the lipid bilayer. The exposing causes the moving component of the molecule to move and thereby open the lipid bilayer (e.g., by pore formation). The external stimuli may include an energy source, such as ultraviolet light. The opened lipid bilayer may be a component of cell membranes in vitro or in vivo . The opening of the lipid bilayer may allow for the passage of various materials (e.g., active agents, such as peptide -based drugs) through the lipid bilayer and into cells. Additional embodiments of the present disclosure pertain to the aforementioned molecules for opening lipid bilayers. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11154623-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11565003-B2 |
| priorityDate |
2016-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |