| abstract |
Chickens that selectively produce female offspring are provided. In some aspects, a bird or cells thereof are provided that comprise an autosomal repressor cassette integrated on at least one copy of an autosome, which can suppress the expression of a protein essential for early development. In some aspects, a bird or cells thereof are provided that comprise an ectopic rescue cassette and a repressor cassette on the W or Z chromosome, which can selectively rescue embryo development in progeny animals. Methods for producing such animals and for production of commodity poultry eggs are also provided. |