abstract |
The present invention concerns an antibody, functional fragment, and derivative thereof, which binds specifically to the OAcGD2 ganglioside, said antibody comprising i) a humanized light chain variable region (VL) polypeptide having the amino acid sequence SEQ id n°112; and ii) a humanized heavy chain variable region (VH) having the amino acid sequence SEQ id n°76; and its use in diagnostics and therapy. |