| abstract |
The present invention addresses the problem of providing an evaluation method or the like which is capable of providing highly reliable information which helps one to know the future onset risk of Alzheimer's disease. An embodiment of the present invention evaluates the future onset risk of Alzheimer's disease in a subject to be evaluated, by using one or more of the following concentrations in the blood of a subject to be evaluated who has mild cognitive impairment: α-ABA, Ala, Arg, Asn, Cit, Gln, Glu, Gly, His, Ile, Leu, Lys, Met, Orn, Phe, Pro, Ser, Thr, Trp, Tyr, Val, Cysteine, Taurine, bABA, Ethylglycine, Hypotaurine, 3-Me-His, 5-HydroxyTrp, aAiBA, and N8-Acetylspermidine. |