| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_011a8283b062bdc0ccab7ca23c5f79ab |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2201-129
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6458
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-65 |
| filingDate |
2017-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a7d5b9046c9fd6f9e5923c1a1d7a358
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d5afa28b71b3d52f68b9ac079d57b33 |
| publicationDate |
2018-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018007415-A1 |
| titleOfInvention |
Device and method for the determination of transfection |
| abstract |
The present invention relates to an in vitro method for determining the transfection of a cell or group of cells, wherein said determination is performed spectroscopically. The determination comprises recording at least one Raman spectrum by means of Raman spectroscopy of the cell or group of cells. Furthermore, the present invention relates to a device for determining the transfection of a cell or group of cells, wherein the device comprises as a first unit (i) a microscope system in order to visualize the cells, as a second unit (ii) a Raman spectroscopy system in order to record a Raman spectrum of a cell or group of cells, and as a third unit (iii) an evaluation module which is coupled to the Raman spectroscopy system and which is configured to determine by means of the recorded Raman spectrum whether a cell or group of cells has been transfected. A statistical analysis of the Raman spectral data is disclosed using principal component analysis. In a PCA scores plot, it can be seen that the transfected samples differ from the control samples on the PC-1 axis. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3811052-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111289489-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021130242-A1 |
| priorityDate |
2016-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |